Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D000094504 http://purl.bioontology.org/ontology/MESH/D000094504
Preferred Name	Corneal Cross-Linking
Definitions	An ophthalmic treatment used to prevent weakening or bulging of the CORNEA in corneal ECTASIA, e.g., post-LASIK ectasia, KERATOCONUS and pellucid marginal corneal degeneration. It uses UV-A and RIBOFLAVIN to crosslink and strengthen COLLAGEN fibers within the cornea.
Synonyms	Corneal Cross Linking Epithelium-on Corneal Cross-Linking Epi off Corneal Cross Linking Cross-Linking, Epithelium-off Corneal Corneal Collagen Cross-Linkings Epithelium-on CXL Epithelium-off Corneal Cross-Linking Epi off CXL Corneal Cross-Linking, Epi-off Cross-Linking, Transepithelial Corneal CXL, Epi-off Cross-Linkings, Corneal Collagen Epi-on CXL Corneal Collagen Cross-Linking Transepithelial Corneal Cross Linking Collagen Cross-Linking, Corneal Cross-Linking, Corneal Collagen CXL, Epithelium-off Corneal Collagen Cross Linking Corneal Cross-Linking, Transepithelial Transepithelial Corneal Cross-Linking CXL, Epithelium-on Epi on CXL Epithelium-off Corneal Cross-Linkings Cross-Linking, Epithelium-on Corneal Epi-off CXLs CXL, Transepithelial Transepithelial CXLs Cross-Linking, Epi-off Corneal Epithelium-on Corneal Cross-Linkings Epi-on CXLs CXL, Epi-on Cross-Linking, Corneal Epi-off Corneal Cross-Linking Corneal Cross-Linkings Collagen Cross-Linkings, Corneal Epi-off Corneal Cross-Linkings Epithelium on Corneal Cross Linking Epithelium-off CXL Epithelium-off CXLs Transepithelial CXL Transepithelial Corneal Cross-Linkings Corneal Cross-Linking, Epithelium-on Epithelium-on CXLs Epithelium off CXL Corneal Cross-Linking, Epithelium-off Epithelium on CXL Epi-off CXL Epithelium off Corneal Cross Linking See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	An ophthalmic treatment used to prevent weakening or bulging of the CORNEA in corneal ECTASIA, e.g., post-LASIK ectasia, KERATOCONUS and pellucid marginal corneal degeneration. It uses UV-A and RIBOFLAVIN to crosslink and strengthen COLLAGEN fibers within the cornea.
altLabel	Corneal Cross Linking Epithelium-on Corneal Cross-Linking Epi off Corneal Cross Linking Cross-Linking, Epithelium-off Corneal Corneal Collagen Cross-Linkings Epithelium-on CXL Epithelium-off Corneal Cross-Linking Epi off CXL Corneal Cross-Linking, Epi-off Cross-Linking, Transepithelial Corneal CXL, Epi-off Cross-Linkings, Corneal Collagen Epi-on CXL Corneal Collagen Cross-Linking Transepithelial Corneal Cross Linking Collagen Cross-Linking, Corneal Cross-Linking, Corneal Collagen CXL, Epithelium-off Corneal Collagen Cross Linking Corneal Cross-Linking, Transepithelial Transepithelial Corneal Cross-Linking CXL, Epithelium-on Epi on CXL Epithelium-off Corneal Cross-Linkings Cross-Linking, Epithelium-on Corneal Epi-off CXLs CXL, Transepithelial Transepithelial CXLs Cross-Linking, Epi-off Corneal Epithelium-on Corneal Cross-Linkings Epi-on CXLs CXL, Epi-on Cross-Linking, Corneal Epi-off Corneal Cross-Linking Corneal Cross-Linkings Collagen Cross-Linkings, Corneal Epi-off Corneal Cross-Linkings Epithelium on Corneal Cross Linking Epithelium-off CXL Epithelium-off CXLs Transepithelial CXL Transepithelial Corneal Cross-Linkings Corneal Cross-Linking, Epithelium-on Epithelium-on CXLs Epithelium off CXL Corneal Cross-Linking, Epithelium-off Epithelium on CXL Epi-off CXL Epithelium off Corneal Cross Linking See more See less
prefLabel	Corneal Cross-Linking
Machine permutation	2023
HN	2023
type	http://www.w3.org/2002/07/owl#Class
tui	T061
TERMUI	T001119440 T001119438 T001119439 T001119437 T001119441 T001119443 T001119442 T001119435 T001120195 T001119444 T001119436 See more See less
TH	NLM (2023)
MMR	20230101
notation	D000094504
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T061
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000379 http://purl.bioontology.org/ontology/MESH/Q000706 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000941 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000295 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000639 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000401 See more See less
DX	20230101
cui	C5690811 C5690810 C5690809 C4065848
DC	1
MN	E02.186.500.500 E02.319.685.500 E02.774.722.218
AQL	AE CL EC ES HI IS MO MT NU PX SN ST TD VE
MDA	20220330
subClassOf	http://purl.bioontology.org/ontology/MESH/D010778

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