Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D000094242
http://purl.bioontology.org/ontology/MESH/D000094242
Preferred Name

Medium Spiny Neurons
Definitions
Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE.
Synonyms
Striatal Medium-Sized Spiny Neurons
Medium Spiny Neuron
Striatal Medium Sized Spiny Neurons
Neuron, Medium Spiny
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE.
altLabel
Striatal Medium-Sized Spiny Neurons
Medium Spiny Neuron
Striatal Medium Sized Spiny Neurons
Neuron, Medium Spiny
prefLabel
Medium Spiny Neurons
Machine permutation
2023
HN
2023
type
tui
T025
TERMUI
T001118807
T001118808
TH
NLM (2023)
MMR
20230101
notation
D000094242
Inverse of RO
Semantic type UMLS property
Inverse of AQ
FX
D003342
DX
20230101
cui
C5690793
DC
1
MN
A08.675.289.500
A11.671.285.500
A08.675.650.535
A11.671.650.535
AQL
CH CL CY DE EN IM ME MI PA PH PS RE TR UL VI
MDA
20220315
subClassOf
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