Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D000092223 http://purl.bioontology.org/ontology/MESH/D000092223
Preferred Name	Hippocampal Sclerosis
Definitions	Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY.
Synonyms	Hippocampal Sclerosis, CA1 Aging Hippocampal Scleroses Horn Sclerosis, Ammon CA1 Hippocampal Scleroses Sclerosis, Endfolium Sclerosis, Ammon Horn Endfolium Sclerosis Ammon Horn Sclerosis Endfolium Scleroses Sclerosis, Hippocampal CA4 Hippocampal Scleroses Hippocampal Sclerosis, CA4 CA1 Hippocampal Sclerosis Scleroses, Mesial Temporal Hippocampal Scleroses Aging Hippocampal Sclerosis Sclerosis, CA1 Hippocampal Sclerosis, Mesial Temporal Ammon Horn Scleroses CA4 Hippocampal Sclerosis Hippocampal Sclerosis of Aging Mesial Temporal Sclerosis Sclerosis, CA4 Hippocampal See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY.
altLabel	Hippocampal Sclerosis, CA1 Aging Hippocampal Scleroses Horn Sclerosis, Ammon CA1 Hippocampal Scleroses Sclerosis, Endfolium Sclerosis, Ammon Horn Endfolium Sclerosis Ammon Horn Sclerosis Endfolium Scleroses Sclerosis, Hippocampal CA4 Hippocampal Scleroses Hippocampal Sclerosis, CA4 CA1 Hippocampal Sclerosis Scleroses, Mesial Temporal Hippocampal Scleroses Aging Hippocampal Sclerosis Sclerosis, CA1 Hippocampal Sclerosis, Mesial Temporal Ammon Horn Scleroses CA4 Hippocampal Sclerosis Hippocampal Sclerosis of Aging Mesial Temporal Sclerosis Sclerosis, CA4 Hippocampal See more See less
prefLabel	Hippocampal Sclerosis
Machine permutation	2023
HN	2023
type	http://www.w3.org/2002/07/owl#Class
tui	T047
TERMUI	T001110876 T001110879 T001110884 T001110883 T001124779 T001110877 T001110882 See more See less
TH	NLM (2023) NLM (2024)
MMR	20230426
notation	D000092223
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T047
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000662 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000523 http://purl.bioontology.org/ontology/MESH/Q000401 See more See less
DX	20230101
cui	C2062593 C1504404 C5691286 C5690728 C5691287
DC	1
MN	C16.131.666.507.400.187 C10.500.507.400.187
AQL	BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VE VI
MDA	20210831
subClassOf	http://purl.bioontology.org/ontology/MESH/D065703

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