Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D000086969 http://purl.bioontology.org/ontology/MESH/D000086969
Preferred Name	Viral Replication Compartments
Definitions	Sites in the host cell where the virus induces the formation of cellular assemblies for the replication of the VIRAL GENOME. Cytoplasmic, virus-induced membrane structures, derived from host cell organelles, that house the replication and transcription enzyme complexes of POSITIVE-STRAND RNA VIRUSES. Cytoplasmic, virus-induced double-membrane structures, derived from ENDOPLASMIC RETICULUM or GOLGI APPARATUS, that house the replication and transcription enzyme complexes of NIDOVIRALES and PICORNAVIRIDAE. Double-membrane vesicles that are interconnected by their outer membranes and where coronavirus transcription and replication occur. They are derived from and contiguous with the ENDOPLASMIC RETICULUM. Subnuclear compartments formed from a reorganization of the nuclear architecture induced by BACULOVIRUSES.
Synonyms	Positive Strand RNA Virus Replication Transcription Complexes Virus-Induced Double-Membrane Vesicle Coronavirus Replication-Transcription Compartment Replication Compartments, Virus Double-Membrane Vesicles, Virus-Induced Virus Induced Double Membrane Vesicles Double Membrane Vesicles, Virus Induced Coronavirus Double-Membrane Vesicle Viral Replication Center Replication Center, Viral Vesicles, Virus-Induced Double-Membrane Coronavirus Double-Membrane Vesicles Double-Membrane Vesicle, Virus-Induced Coronavirus Replication Transcription Complexes Double-Membrane Vesicle, Coronavirus Positive-Strand RNA Virus Replication-Transcription Compartments Viral Replication Centers Coronavirus Replication-Transcription Complexes Complexe, Coronavirus Replication-Transcription Viral Factory Replication-Transcription Compartments, Coronavirus Coronavirus RTCs Coronavirus Replication-Transcription Compartments Virus Factories Replication Compartment, Virus Vesicle, Coronavirus Double-Membrane Replication-Transcription Compartment, Coronavirus Coronavirus Double Membrane Vesicles Replication-Transcription Complexes, Coronavirus Replication Compartment, Viral Vesicle, Virus-Induced Double-Membrane Complexes, Coronavirus Replication-Transcription Coronavirus RTC Viroplasm Positive Strand RNA Virus Replication-Transcription Complexes Virus Replication Centers Virus Replication Compartment Coronavirus Replication Transcription Compartments Virus-Induced Double-Membrane Vesicles Virus Replication Center Viral Factories Replication Compartments, Viral Double-Membrane Vesicles, Coronavirus Virus Factory Zippered Endoplasmic Reticulum Double Membrane Spherules Virus Replication Compartments Viral Replication Compartment Replication Centers, Virus Virogenic Stroma Replication Center, Virus Vesicles, Coronavirus Double-Membrane Replication Centers, Viral Zippered Endoplasmic Reticulum Double-Membrane Spherules Positive Strand RNA Virus Replication Transcription Compartments See more See less
Type	http://www.w3.org/2002/07/owl#Class

definition	Sites in the host cell where the virus induces the formation of cellular assemblies for the replication of the VIRAL GENOME. Cytoplasmic, virus-induced membrane structures, derived from host cell organelles, that house the replication and transcription enzyme complexes of POSITIVE-STRAND RNA VIRUSES. Cytoplasmic, virus-induced double-membrane structures, derived from ENDOPLASMIC RETICULUM or GOLGI APPARATUS, that house the replication and transcription enzyme complexes of NIDOVIRALES and PICORNAVIRIDAE. Double-membrane vesicles that are interconnected by their outer membranes and where coronavirus transcription and replication occur. They are derived from and contiguous with the ENDOPLASMIC RETICULUM. Subnuclear compartments formed from a reorganization of the nuclear architecture induced by BACULOVIRUSES.
altLabel	Positive Strand RNA Virus Replication Transcription Complexes Virus-Induced Double-Membrane Vesicle Coronavirus Replication-Transcription Compartment Replication Compartments, Virus Double-Membrane Vesicles, Virus-Induced Virus Induced Double Membrane Vesicles Double Membrane Vesicles, Virus Induced Coronavirus Double-Membrane Vesicle Viral Replication Center Replication Center, Viral Vesicles, Virus-Induced Double-Membrane Coronavirus Double-Membrane Vesicles Double-Membrane Vesicle, Virus-Induced Coronavirus Replication Transcription Complexes Double-Membrane Vesicle, Coronavirus Positive-Strand RNA Virus Replication-Transcription Compartments Viral Replication Centers Coronavirus Replication-Transcription Complexes Complexe, Coronavirus Replication-Transcription Viral Factory Replication-Transcription Compartments, Coronavirus Coronavirus RTCs Coronavirus Replication-Transcription Compartments Virus Factories Replication Compartment, Virus Vesicle, Coronavirus Double-Membrane Replication-Transcription Compartment, Coronavirus Coronavirus Double Membrane Vesicles Replication-Transcription Complexes, Coronavirus Replication Compartment, Viral Vesicle, Virus-Induced Double-Membrane Complexes, Coronavirus Replication-Transcription Coronavirus RTC Viroplasm Positive Strand RNA Virus Replication-Transcription Complexes Virus Replication Centers Virus Replication Compartment Coronavirus Replication Transcription Compartments Virus-Induced Double-Membrane Vesicles Virus Replication Center Viral Factories Replication Compartments, Viral Double-Membrane Vesicles, Coronavirus Virus Factory Zippered Endoplasmic Reticulum Double Membrane Spherules Virus Replication Compartments Viral Replication Compartment Replication Centers, Virus Virogenic Stroma Replication Center, Virus Vesicles, Coronavirus Double-Membrane Replication Centers, Viral Zippered Endoplasmic Reticulum Double-Membrane Spherules Positive Strand RNA Virus Replication Transcription Compartments See more See less
prefLabel	Viral Replication Compartments
Machine permutation	2021
HN	2021
type	http://www.w3.org/2002/07/owl#Class
tui	T026
TERMUI	T001081375 T001081378 T001081383 T001081382 T001080920 T001081427 T001081379 T001081374 T001080919 T001081431 T001080905 T001081372 T001083208 T001081373 T001081377 T001081430 T001080921 T001081376 T001080906 See more See less
TH	NLM (2021)
MMR	20210101
notation	D000086969
Inverse of RO	http://purl.bioontology.org/ontology/MESH/D014779
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T026
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
FX	D014779
DX	20210101
cui	C5392158 C5392876 C5392875 C5392877 C4083021 C3820746 C5392874 C5392159 See more See less
DC	1
MN	G06.920.400.500 A11.284.420.390.500
AQL	CH CL DE EN IM ME PA PH RE UL
MDA	20200518
subClassOf	http://purl.bioontology.org/ontology/MESH/D007181

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