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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D000077545
http://purl.bioontology.org/ontology/MESH/D000077545
|
|---|---|
| Preferred Name | Eplerenone |
| Definitions |
A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION.
|
| Synonyms |
9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra
Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A spironolactone derivative and selective ALDOSTERONE RECEPTOR antagonist that is used in the management of HYPERTENSION and CONGESTIVE HEART FAILURE, post-MYOCARDIAL INFARCTION. |
|---|---|
| altLabel | 9,11-Epoxy-7-(methoxycarbonyl)-3-oxo-17-pregn-4-ene-21,17-carbolactone
Eplerenon
Inspra
Spiro(cyclopenta(7,8)phenanthro(4b,5-b)oxirene-7(3H),2'(3'H)-furan)-10-carboxylic acid, 2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2,5'-dioxo-, methyl ester, (4aS,4bR,5aR,6aS,7 R,9aS,9bR,10R)-
|
| prefLabel | Eplerenone
|
| Machine permutation | 2019; EPLERENONE was indexed under SPIRONOLACTONE/analogs&derivatives 2000-2018
|
| HN | 2019 (2000)
|
| type | |
| isa | |
| PA |
D000959
D000451
|
| tui |
T109
T121
|
| TERMUI |
T000940100
T522479
T000940099
T000940102
|
| TH |
US
NLM (2009)
NLM (2000)
FDA SRS (2014)
USAN (19XX)
INN (19XX)
NLM (2010)
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|
| MMR | 20190101
|
| notation | D000077545
|
| Semantic type UMLS property | |
| Inverse of AQ |
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|
| DX | 20190101
|
| cui |
C1144054
C0961485
|
| DC | 1
|
| MN |
D02.540.383
D04.210.500.745.745.329
|
| LT | TRD
|
| AQL | AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
| Inverse of RB |
0
6995V82D0B
|
| MDA | 20180206
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |