Preferred Name | Decitabine | |
Synonyms |
NSC127716 5AzadC NSC-127716 2' Deoxy 5 azacytidine 2'-Deoxy-5-azacytidine 5 Aza 2' deoxycytidine AzadC Compound Mesylate, Decitabine 5-Deoxyazacytidine Dacogen 5-AzadC 5 Deoxyazacytidine Decitabine Mesylate 5-Azadeoxycytidine Compound, AzadC 5-Aza-2'-deoxycytidine 5 Azadeoxycytidine NSC 127716 |
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Definitions |
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA. |
|
ID |
http://purl.bioontology.org/ontology/MESH/D000077209 |
|
altLabel |
NSC127716 5AzadC NSC-127716 2' Deoxy 5 azacytidine 2'-Deoxy-5-azacytidine 5 Aza 2' deoxycytidine AzadC Compound Mesylate, Decitabine 5-Deoxyazacytidine Dacogen 5-AzadC 5 Deoxyazacytidine Decitabine Mesylate 5-Azadeoxycytidine Compound, AzadC 5-Aza-2'-deoxycytidine 5 Azadeoxycytidine NSC 127716 |
|
AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
cui |
C2001355 C0049065 C0950333 C1712036 |
|
DC |
1 |
|
definition |
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA. |
|
DX |
20190101 |
|
FX |
D003561 |
|
HN |
2019 (1977) |
|
Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
Inverse of RB |
776B62CQ27 6U3LPL9PRN 0 |
|
Inverse of RO | ||
isa | ||
LT |
TRD |
|
Machine permutation |
2019; DECITABINE was indexed under AZACITIDINE 1981-2018, and under DEOXYCITIDNE 1977-1980 |
|
Mapped from | ||
MDA |
20180709 |
|
MMR |
20180702 |
|
MN |
D02.145.150.500 D13.570.800.286.300.500 D03.383.742.680.245.217.500 D13.570.685.245.217.500 |
|
notation |
D000077209 |
|
PA |
D004791 D000964 |
|
prefLabel |
Decitabine |
|
RR |
2353-33-5 (Decitabine) 6U3LPL9PRN |
|
TERMUI |
T092825 T000937672 T673110 T000938328 T000938327 T000937668 T000937670 T092824 T000937669 T000937671 T000937673 T000937674 |
|
TH |
NLM (1977) FDA SRS (2013) NLM (2015) NLM (2019) USAN (19XX) INN (19XX) NLM (2006) FDA SRS (2015) |
|
tui |
T114 T121 |
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subClassOf |