Medical Subject Headings

Last uploaded: August 28, 2024
Preferred Name

Decitabine
Synonyms

NSC127716

5AzadC

NSC-127716

2' Deoxy 5 azacytidine

2'-Deoxy-5-azacytidine

5 Aza 2' deoxycytidine

AzadC Compound

Mesylate, Decitabine

5-Deoxyazacytidine

Dacogen

5-AzadC

5 Deoxyazacytidine

Decitabine Mesylate

5-Azadeoxycytidine

Compound, AzadC

5-Aza-2'-deoxycytidine

5 Azadeoxycytidine

NSC 127716

Definitions

An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

ID

http://purl.bioontology.org/ontology/MESH/D000077209

altLabel

NSC127716

5AzadC

NSC-127716

2' Deoxy 5 azacytidine

2'-Deoxy-5-azacytidine

5 Aza 2' deoxycytidine

AzadC Compound

Mesylate, Decitabine

5-Deoxyazacytidine

Dacogen

5-AzadC

5 Deoxyazacytidine

Decitabine Mesylate

5-Azadeoxycytidine

Compound, AzadC

5-Aza-2'-deoxycytidine

5 Azadeoxycytidine

NSC 127716

AQL

AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR

cui

C2001355

C0049065

C0950333

C1712036

DC

1

definition

An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

DX

20190101

FX

D003561

HN

2019 (1977)

Inverse of AQ

http://purl.bioontology.org/ontology/MESH/Q000097

http://purl.bioontology.org/ontology/MESH/Q000627

http://purl.bioontology.org/ontology/MESH/Q000493

http://purl.bioontology.org/ontology/MESH/Q000494

http://purl.bioontology.org/ontology/MESH/Q000276

http://purl.bioontology.org/ontology/MESH/Q000138

http://purl.bioontology.org/ontology/MESH/Q000134

http://purl.bioontology.org/ontology/MESH/Q000266

http://purl.bioontology.org/ontology/MESH/Q000378

http://purl.bioontology.org/ontology/MESH/Q000008

http://purl.bioontology.org/ontology/MESH/Q000009

http://purl.bioontology.org/ontology/MESH/Q000031

http://purl.bioontology.org/ontology/MESH/Q000032

http://purl.bioontology.org/ontology/MESH/Q000037

http://purl.bioontology.org/ontology/MESH/Q000191

http://purl.bioontology.org/ontology/MESH/Q000302

http://purl.bioontology.org/ontology/MESH/Q000145

http://purl.bioontology.org/ontology/MESH/Q000592

http://purl.bioontology.org/ontology/MESH/Q000737

http://purl.bioontology.org/ontology/MESH/Q000819

http://purl.bioontology.org/ontology/MESH/Q000506

http://purl.bioontology.org/ontology/MESH/Q000633

http://purl.bioontology.org/ontology/MESH/Q000600

http://purl.bioontology.org/ontology/MESH/Q000652

http://purl.bioontology.org/ontology/MESH/Q000528

Inverse of RB

776B62CQ27

6U3LPL9PRN

0

Inverse of RO

http://purl.bioontology.org/ontology/MESH/D003561

isa

http://purl.bioontology.org/ontology/MESH/D000964

http://purl.bioontology.org/ontology/MESH/D004791

LT

TRD

Machine permutation

2019; DECITABINE was indexed under AZACITIDINE 1981-2018, and under DEOXYCITIDNE 1977-1980

Mapped from

http://purl.bioontology.org/ontology/MESH/C000723076

MDA

20180709

MMR

20180702

MN

D02.145.150.500

D13.570.800.286.300.500

D03.383.742.680.245.217.500

D13.570.685.245.217.500

notation

D000077209

PA

D004791

D000964

prefLabel

Decitabine

RR

2353-33-5 (Decitabine)

6U3LPL9PRN

TERMUI

T092825

T000937672

T673110

T000938328

T000938327

T000937668

T000937670

T092824

T000937669

T000937671

T000937673

T000937674

TH

NLM (1977)

FDA SRS (2013)

NLM (2015)

NLM (2019)

USAN (19XX)

INN (19XX)

NLM (2006)

FDA SRS (2015)

tui

T114

T121

subClassOf

http://purl.bioontology.org/ontology/MESH/D001374

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/NDFRT/N0000179023 NDFRT CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077209 MSHFRE CUI
http://purl.bioontology.org/ontology/RXNORM/636242 RXNORM CUI
http://purl.bioontology.org/ontology/NDFRT/N0000175993 NDFRT CUI
http://purl.bioontology.org/ontology/ATC/L01BC08 ATC CUI
http://purl.bioontology.org/ontology/RXNORM/15657 RXNORM CUI
http://purl.bioontology.org/ontology/SNOMEDCT/420759005 SNOMEDCT CUI
http://purl.bioontology.org/ontology/SCTSPA/420517007 SCTSPA CUI
http://purl.bioontology.org/ontology/SCTSPA/420759005 SCTSPA CUI
http://purl.bioontology.org/ontology/NDDF/011499 NDDF CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039299 PDQ CUI
http://purl.bioontology.org/ontology/SNOMEDCT/420517007 SNOMEDCT CUI
http://purl.bioontology.org/ontology/VANDF/4025438 VANDF CUI
http://purl.bioontology.org/ontology/MSHFRE/D000077209 MSHFRE CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000039299 PDQ CUI
http://purl.bioontology.org/ontology/NDFRT/N0000175993 NDFRT LOOM
http://purl.obolibrary.org/obo/DRON_00016646 PDRO LOOM
http://purl.bioontology.org/ontology/ATC/L01BC08 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0049065 OCHV LOOM
http://purl.bioontology.org/ontology/RXNORM/15657 RXNORM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026286 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C981 BERO LOOM
http://purl.obolibrary.org/obo/dinto_DB01262 DINTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C981 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/420759005 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB01262 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C014347 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/011499 NDDF LOOM
http://www.drugbank.ca/drugs/DB01262 FTC LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039299 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4025438 VANDF LOOM