Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D000077022
http://purl.bioontology.org/ontology/MESH/D000077022
Preferred Name

Survivin

Definitions
An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.
Synonyms
Baculoviral IAP Repeat containing Protein 5
BIRC5 Protein
Baculoviral IAP Repeat-containing Protein 5
Type http://www.w3.org/2002/07/owl#Class
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