Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D000076249
http://purl.bioontology.org/ontology/MESH/D000076249
Preferred Name

Heat Shock Transcription Factors

Definitions
Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3' pentamer DNA sequences and are regulated by POLY-ADP-RIBOSYLATION. They play essential roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.
Synonyms
Heat Stress Transcription Factor
Plant Heat Shock Factor
Plant Heat Shock Factors
Heat Shock Factor, Plant
Heat Shock Transcription Factor 1
Heat Shock Transcription Factor
Heat Stress Transcription Factors
Heat Shock Factor Protein 1
Type http://www.w3.org/2002/07/owl#Class
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