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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D000074662
http://purl.bioontology.org/ontology/MESH/D000074662
|
|---|---|
| Preferred Name | NADPH Oxidase 2 |
| Definitions |
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
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| Synonyms |
GP91 PHOX Protein
Cytochrome B 245 Beta Chain
NOX2 Protein
Oxidase 2, NADPH
CYBB Protein
GP91-PHOX Protein
Cytochrome B-245 Beta Chain
Chronic Granulomatous Disease Protein
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. |
|---|---|
| altLabel |
GP91 PHOX Protein
Cytochrome B 245 Beta Chain
NOX2 Protein
Oxidase 2, NADPH
CYBB Protein
GP91-PHOX Protein
Cytochrome B-245 Beta Chain
Chronic Granulomatous Disease Protein
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|
| prefLabel | NADPH Oxidase 2
|
| Machine permutation | 2018
|
| HN | 2018
|
| Mapped from | |
| type | |
| tui |
T116
T123
|
| TERMUI |
T000916828
T000916832
T000916830
T000916831
T000916833
T000916829
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|
| TH | NLM (2018)
|
| MMR | 20180101
|
| notation | D000074662
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| Semantic type UMLS property | |
| Inverse of AQ |
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|
| DX | 20180101
|
| cui | C4319655
|
| DC | 1
|
| MN |
D08.811.682.608.575.875
D12.776.543.653.875
D12.776.331.894.875
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| AQL | AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
|
| Inverse of RB | EC 1.6.3.-
|
| MDA | 20170306
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |