Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D000072105 http://purl.bioontology.org/ontology/MESH/D000072105
Preferred Name	Superoxide Dismutase-1
Definitions	A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
Synonyms	SOD1 Protein Cu-Zn Superoxide Dismutase Superoxide Dismutase, Cu-Zn Superoxide Dismutase, Cuprozinc Cuprozinc Superoxide Dismutase SOD-1 Protein Superoxide Dismutase 1 Cu Zn Superoxide Dismutase SOD 1 Protein
Type	http://www.w3.org/2002/07/owl#Class

definition	A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
altLabel	SOD1 Protein Cu-Zn Superoxide Dismutase Superoxide Dismutase, Cu-Zn Superoxide Dismutase, Cuprozinc Cuprozinc Superoxide Dismutase SOD-1 Protein Superoxide Dismutase 1 Cu Zn Superoxide Dismutase SOD 1 Protein See more See less
prefLabel	Superoxide Dismutase-1
Machine permutation	2017; SUPEROXIDE DISMUTASE -1 was indexed under SUPEROXIDE DISMUTASE 1998-2016; for CU-ZN SUPEROXIDE DISMUTASE, see SUPEROXIDE DISMUTASE 1983-2016
HN	2017 (1998); for CU-ZN SUPEROXIDE DISMUTASE, use SUPEROXIDE DISMUTASE 1983-2016
Mapped from	http://purl.bioontology.org/ontology/MESH/C000606290 http://purl.bioontology.org/ontology/MESH/C000606291 http://purl.bioontology.org/ontology/MESH/C000606292
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T126
TERMUI	T000898140 T039552 T000898138 T000898139 T039551 T000898141 See more See less
TH	NLM (2005) UNK (19XX) NLM (1998) NLM (2017)
MMR	20170101
notation	D000072105
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T126 http://purl.bioontology.org/ontology/STY/T116
RR	EC 1.15.1.1
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20170101
cui	C0669516
DC	1
MN	D08.811.682.881.500
AQL	AD AE AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	EC 1.15.1.1
MDA	20160401
subClassOf	http://purl.bioontology.org/ontology/MESH/D013482

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