Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/D000072100 http://purl.bioontology.org/ontology/MESH/D000072100
Preferred Name	Jagged-1 Protein
Definitions	A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
Synonyms	Serrate-1 Protein Serrate 1 Protein Serrate1 Protein Antigen, CD339 Jagged 1 Jagged1 Protein Jagged 1 Protein CD339 Antigen Jagged-1 Alagille Syndrome Protein
Type	http://www.w3.org/2002/07/owl#Class

definition	A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
altLabel	Serrate-1 Protein Serrate 1 Protein Serrate1 Protein Antigen, CD339 Jagged 1 Jagged1 Protein Jagged 1 Protein CD339 Antigen Jagged-1 Alagille Syndrome Protein See more See less
prefLabel	Jagged-1 Protein
Machine permutation	2017; JAGGED-1 PROTEIN was indexed under CALCIUM-BINDING PROTEINS; MEMBRANE PROTEINS; AND INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1991-2016
HN	2017 (1991)
Mapped from	http://purl.bioontology.org/ontology/MESH/C000606273 http://purl.bioontology.org/ontology/MESH/C000606280 http://purl.bioontology.org/ontology/MESH/C000606276 http://purl.bioontology.org/ontology/MESH/C000606274 http://purl.bioontology.org/ontology/MESH/C000606275 http://purl.bioontology.org/ontology/MESH/C000606278 See more See less
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T192
TERMUI	T000898092 T000898097 T000898094 T000898093 T000898090 T000898096 T000898095 See more See less
TH	NLM (1991) NLM (2005) NLM (2017)
MMR	20170524
notation	D000072100
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T116 http://purl.bioontology.org/ontology/STY/T192
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528 See more See less
DX	20170101
cui	C4085258
DC	1
MN	D12.644.276.930.500 D12.776.157.125.797.500 D23.529.930.500 D12.776.543.800.500
AQL	AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
Inverse of RB	0
MDA	20160401
subClassOf	http://purl.bioontology.org/ontology/MESH/D000072099

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