Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D000071736
http://purl.bioontology.org/ontology/MESH/D000071736
Preferred Name

Stromal Interaction Molecules

Definitions
Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.
Synonyms
Stromal Interaction Molecule
Molecule, Stromal Interaction
Interaction Molecule, Stromal
Type http://www.w3.org/2002/07/owl#Class
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