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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D000071186
http://purl.bioontology.org/ontology/MESH/D000071186
|
|---|---|
| Preferred Name | Beclin-1 |
| Definitions |
An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.
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| Synonyms |
GT197 Protein
Coiled-coil Myosin-like Bcl2-interacting Protein
Beclin1
Beclin 1 Protein
Beclin 1
ATG-6 Protein
ATG 6 Protein
Coiled coil Myosin like Bcl2 interacting Protein
Beclin-1 Protein
ATG6 Protein
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN. |
|---|---|
| altLabel |
GT197 Protein
Coiled-coil Myosin-like Bcl2-interacting Protein
Beclin1
Beclin 1 Protein
Beclin 1
ATG-6 Protein
ATG 6 Protein
Coiled coil Myosin like Bcl2 interacting Protein
Beclin-1 Protein
ATG6 Protein
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| prefLabel | Beclin-1
|
| Machine permutation | 2017
|
| HN | 2017
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| Mapped from |
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| type | |
| tui | T116
|
| TERMUI |
T000893473
T000893474
T000893471
T000893472
T000893476
T000893475
T000893477
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| TH | NLM (2017)
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| MMR | 20170101
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| notation | D000071186
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| Semantic type UMLS property | |
| Inverse of AQ |
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| DX | 20170101
|
| cui | C4255099
|
| DC | 1
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| MN |
D12.776.476.075.335
D12.644.360.075.335
D12.776.094.500
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| AQL | AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR
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| Inverse of RB | 0
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| MDA | 20160111
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |