Link to this page
Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/D000070818
http://purl.bioontology.org/ontology/MESH/D000070818
|
|---|---|
| Preferred Name | Discoidin Domain Receptors |
| Definitions |
Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.
|
| Synonyms |
Receptor, Discoidin Domain
Proteins, DDR
DDR Proteins
Receptors, Discoidin Domain
Discoidin Domain Receptor
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX. |
|---|---|
| altLabel |
Receptor, Discoidin Domain
Proteins, DDR
DDR Proteins
Receptors, Discoidin Domain
Discoidin Domain Receptor
|
| prefLabel | Discoidin Domain Receptors
|
| Machine permutation | 2017; DISCOIDIN DOMAIN RECEPTORS was indexed under RECEPTORS, MITOGEN and RECEPTOR PROTEIN-TYROSINE KINASES 1999-2016
|
| HN | 2017 (1999)
|
| type | |
| tui |
T116
T126
T192
|
| TERMUI |
T000891429
T000891428
T000891432
|
| TH |
NLM (1999)
NLM (2017)
|
| MMR | 20210521
|
| notation | D000070818
|
| Semantic type UMLS property | |
| Inverse of AQ |
See more
See less
|
| DX | 20170101
|
| cui | C0285094
|
| DC | 1
|
| MN |
D12.776.543.750.685.050
D08.811.913.696.620.682.725.400.005
D12.776.476.568.400.005
D12.776.543.750.705.880.300
D12.776.543.750.630.005
|
| AQL | AD AG AI AN BI BL CH CL DE DF GE HI IM IP ME PH RE TU UL
|
| Inverse of RB | EC 2.7.10.1
|
| MDA | 20151201
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |