loading...| Preferred Name |
Omalizumab |
|
| Synonyms |
Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer |
|
| Definitions |
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000069444 |
|
| altLabel |
Immunoglobulin G, anti-(human immunoglobulin E Fc region)(human-mouse monoclonal E25 clone pSVIE26 gamma-chain), disulfide with human-mouse monoclonal E25 clone pSVIE26 kappa-chain, dimer Xolair |
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PK PO RE TO TU UL UR |
|
| cui |
C0966225 C1174773 |
|
| DC |
1 |
|
| definition |
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA. |
|
| DX |
20160101 |
|
| HN |
2016 (2001) |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 |
|
| Inverse of RB |
2P471X1Z11 0 |
|
| isa | ||
| LT |
TRD |
|
| Machine permutation |
2016; OMALIZUMAB was indexed under ANTIBODIES, ANTI-IDIOTYPIC and ANTIBODIES, MONOCLONAL, HUMANIZED 2011-2015; and under ANTIBODIES, MONOCLONAL 2001-2011 |
|
| MDA |
20150701 |
|
| MMR |
20170620 |
|
| MN |
D12.776.124.790.651.114.224.060.844 D12.776.124.486.485.114.071.500 D12.776.124.486.485.114.224.060.844 D12.776.377.715.548.114.071.500 D12.776.377.715.548.114.224.200.844 D12.776.124.790.651.114.071.500 |
|
| notation |
D000069444 |
|
| PA |
D018927 D018926 |
|
| prefLabel |
Omalizumab |
|
| RR |
242138-07-4 |
|
| TERMUI |
T000879977 T534977 |
|
| TH |
US NLM (2001) USAN (19XX) AU FDA SRS (2015) |
|
| tui |
T116 T129 T121 |
|
| subClassOf |