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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D000068582
http://purl.bioontology.org/ontology/MESH/D000068582
|
|---|---|
| Preferred Name | Certolizumab Pegol |
| Definitions |
A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
|
| Synonyms |
Cimzia
CDP 870
CDP870
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. |
|---|---|
| altLabel |
Cimzia
CDP 870
CDP870
|
| prefLabel |
Certolizumab Pegol
|
| TH |
NLM (2002)
FDA SRS (2013)
NLM (2012)
USAN (19XX)
NLM (2007)
|
| notation |
D000068582
|
| RR |
428863-50-7
|
| DX |
20160101
|
| Machine permutation |
2016; CERTILIZUMAB PEGOL was indexed under IMMUNOGLOBULIN FAB FRAGMENTS 2003-2015, POLYETHYLENE GLYCOLS 2003-2015, and under ANTIBODIES, MONOCLONAL, HUMANIZED 2003-2015
|
| MN |
D12.644.541.500.650.250
D12.776.377.715.548.680.650.250
D12.776.124.790.651.680.650.250
D05.750.741.125
D12.776.124.486.485.680.650.250
D12.776.377.715.548.114.224.200.500
D12.776.124.486.485.114.224.060.500
D12.776.124.790.651.114.224.060.500
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|
| PA |
D018501
D000079424
D007166
|
| FX |
D014409
|
| MMR |
20210701
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PK PO RE TO TU UL UR
|
| HN |
2016 (2003)
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
UMD07X179E
0
|
| LT |
TRD
|
| DC |
1
|
| MDA |
20150710
|
| Inverse of RO | |
| type | |
| tui |
T116
T129
T121
|
| cui |
C1172157
C1872109
C2343521
|
| isa | |
| Inverse of AQ |
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|
| TERMUI |
T526396
T526395
T794930
T000876351
|
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