Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/C588087 http://purl.bioontology.org/ontology/MESH/C588087
Preferred Name	2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Synonyms	AMG 232
Type	http://www.w3.org/2002/07/owl#Class

altLabel	AMG 232
prefLabel	2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
II	D000970
Scope Statement	inhibits the interaction between p53 and MDM2; structure in first source
type	http://www.w3.org/2002/07/owl#Class
tui	T109 T121
HM	D000085 D010881
SC	1
TERMUI	T859114 T859115
TH	NLM (2014)
SRC	J Med Chem. 2014 Feb 27;57(4):1454-72.
MMR	20140427
notation	C588087
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T109
cui	C3850402 C3852521
MeSH Frequency	12
DSC	20140427
Inverse of RB	0
Mapped to	http://purl.bioontology.org/ontology/MESH/D000085 http://purl.bioontology.org/ontology/MESH/D010881
MDA	20140427

Delete	Subject	Author	Type	Created
No notes to display