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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/C499671
http://purl.bioontology.org/ontology/MESH/C499671
|
|---|---|
| Preferred Name | aplaviroc |
| Synonyms |
rac-4-(4-((1-butyl-3-(cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro(5.5)undec-9-yl)methyl)phenoxy)benzoic acid
benzoic acid, 4-(4-(((3R)-1-butyl-3-((R)-cyclohexylhydroxymethyl)-2,5-dioxo-1,4,9- triazaspiro(55)undec-9-yl)methyl)phenoxy)-
4-((4-(((3R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro(5.5)undec-9-yl)methyl)phenyl)oxy)benzoic acid hydrochloride
GW873140
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | rac-4-(4-((1-butyl-3-(cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro(5.5)undec-9-yl)methyl)phenoxy)benzoic acid
benzoic acid, 4-(4-(((3R)-1-butyl-3-((R)-cyclohexylhydroxymethyl)-2,5-dioxo-1,4,9- triazaspiro(55)undec-9-yl)methyl)phenoxy)-
4-((4-(((3R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro(5.5)undec-9-yl)methyl)phenyl)oxy)benzoic acid hydrochloride
GW873140
|
|---|---|
| prefLabel | aplaviroc
|
| Scope Statement | a spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1; structure in first source
|
| type | |
| isa | |
| PA | D023581
|
| tui |
T109
T121
|
| HM |
D001565
D013141
D054659
D010879
|
| SC | 1
|
| TERMUI |
T695315
T637001
T672896
T828895
T001091386
|
| TH |
NLM (2005)
FDA SRS (2013)
NLM (2021)
INN (19XX)
NLM (2013)
NLM (2006)
NLM (2007)
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|
| SRC | Mol Pharmacol 2005 Apr;67(4):1268-82
|
| MMR | 20201124
|
| notation | C499671
|
| Semantic type UMLS property | |
| cui |
C1567923
C1567924
C5435399
C3495568
|
| MeSH Frequency | 30
|
| DSC | 20050418
|
| Inverse of RB |
98B425P30V
0
|
| Mapped to | |
| MDA | 20050418
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |