Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/C492300 http://purl.bioontology.org/ontology/MESH/C492300
Preferred Name	Itm2b protein, mouse
Synonyms	mBRI2 protein, mouse integral membrane protein 2B, mouse Bri2 protein, mouse
Type	http://www.w3.org/2002/07/owl#Class

altLabel	mBRI2 protein, mouse integral membrane protein 2B, mouse Bri2 protein, mouse
prefLabel	Itm2b protein, mouse
Scope Statement	a point mutation at the stop codon of BRI results in the generation of the ABri peptide, which is deposited as amyloid fibrils causing neuronal dysfunction and dementia; RefSeq NM_008410
type	http://www.w3.org/2002/07/owl#Class
tui	T116 T123
HM	D048868
SC	1
TERMUI	T591504 T591502 T591503 T591501
TH	NLM (2004)
MMR	20191213
notation	C492300
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T123 http://purl.bioontology.org/ontology/STY/T116
cui	C1452546
MeSH Frequency	31
PI	AMYLOID (2004-2005) Membrane Proteins (2005-2020)
DSC	20041102
Inverse of RB	0
Mapped to	http://purl.bioontology.org/ontology/MESH/D048868
MDA	20041102

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