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Medical Subject Headings
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MESH/C466644
http://purl.bioontology.org/ontology/MESH/C466644
|
|---|---|
| Preferred Name | 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid |
| Synonyms |
lapaquistat
TAK475
(1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid
TAK-475
TAK 475
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | lapaquistat
TAK475
(1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid
TAK-475
TAK 475
|
|---|---|
| prefLabel | 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid
|
| II | D013186/Q000037
|
| Scope Statement | inhibits squalene synthase; structure in first source
|
| type | |
| tui |
T109
T123
|
| HM |
D010880
D010077
|
| SC | 1
|
| TERMUI |
T522870
T522867
T522868
T522869
T723482
T723481
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|
| TH |
NLM (2002)
NLM (2008)
|
| SRC | J Med Chem 2002 Sep 26;45(20):4571-80
|
| MMR | 20080801
|
| notation | C466644
|
| Semantic type UMLS property | |
| cui |
C1144136
C1144550
|
| MeSH Frequency | 18
|
| LT | TRD
|
| DSC | 20021016
|
| Inverse of RB | 0
|
| Mapped to | |
| MDA | 20021016
|
| Delete | Subject | Author | Type | Created |
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| No notes to display |