Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/C108192
http://purl.bioontology.org/ontology/MESH/C108192
Preferred Name

aloxistatin
Synonyms
(2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester
epoxysuccinyl-leucylamide(3-methyl)butane ethyl ester
EP-453
EP 453
loxistatin, (2S-(2alpha,3beta(R*)))-isomer
ethyl (+)-(2S,3S)-2,3-epoxy-N-((S)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate
E64d inhibitor
ethyl epoxysuccinyl-leucylamido-3-methylbutane
loxistatin
protease inhibitor E64d
ethyl 3-(3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate
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Type http://www.w3.org/2002/07/owl#Class

All Properties

altLabel
(2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester
epoxysuccinyl-leucylamide(3-methyl)butane ethyl ester
EP-453
EP 453
loxistatin, (2S-(2alpha,3beta(R*)))-isomer
ethyl (+)-(2S,3S)-2,3-epoxy-N-((S)-1-(isopentylcarbamoyl)-3-methylbutyl)succinamate
E64d inhibitor
ethyl epoxysuccinyl-leucylamido-3-methylbutane
loxistatin
protease inhibitor E64d
ethyl 3-(3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate
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prefLabel
aloxistatin
Scope Statement
a membrane-permeable cysteine protease inhibitor
type
isa
PA
D010975
D015853
tui
T116
T121
Has mapping qualifier
HM
D007930/Q000031
SC
1
TERMUI
T585354
T167445
T585356
T311167
T167451
T167446
T585357
T167448
T585355
T352622
T585353
T167449
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TH
NLM (1997)
NLM (2004)
FDA SRS (2013)
INN (19XX)
SRC
Metabolism 1997 Sep;46(9):1090-4
MMR
20121105
notation
C108192
Semantic type UMLS property
RR
96244-68-7
88321-09-9 (aloxistatin)
cui
C0665866
C0116283
C0902566
MeSH Frequency
131
DSC
19971002
Inverse of RB
96244-68-7
L5W337AOUR
0
Mapped to
MDA
19971002
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