Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/C077100 http://purl.bioontology.org/ontology/MESH/C077100
Preferred Name	FK 453
Synonyms	2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-, (R-(E))- (+)-(R)-(1-(E)-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)acryl)-2-piperidine ethanol FR 113453 FR113453 FR 113452 FR113452
Type	http://www.w3.org/2002/07/owl#Class

altLabel	2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-, (R-(E))- (+)-(R)-(1-(E)-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)acryl)-2-piperidine ethanol FR 113453 FR113453 FR 113452 FR113452 See more See less
prefLabel	FK 453
Scope Statement	adenosine A1 receptor antagonist; structure given in first source; a new antihypertensive agent with diuretic action in isolated rabbit aorta; FR113452 is the S-(-) enantiomer of FK 453
type	http://www.w3.org/2002/07/owl#Class
tui	T109 T121
HM	D011725 D011720
SC	1
TERMUI	T237178 T237180 T237179 T237175 T237176 T237177 See more See less
TH	NLM (1992)
SRC	Pharmacology 1992;44(4):206-14
MMR	20010111
notation	C077100
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T109
cui	C0173133 C0287823 C0173135 C0287824
MeSH Frequency	15
DSC	19921102
Inverse of RB	121524-18-3
Mapped to	http://purl.bioontology.org/ontology/MESH/D011725 http://purl.bioontology.org/ontology/MESH/D011720
MDA	19921102

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