Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/C075995
http://purl.bioontology.org/ontology/MESH/C075995
Preferred Name

down-regulator of transcription 1
Synonyms
NC2 protein, mouse
NC2beta protein, mouse
down-regulator of transcription 1 protein, mouse
negative cofactor 2 beta, human
NC2-beta protein, human
down-regulator of transcription 1, TBP-binding (negative cofactor 2), human
NC2beta protein, human
DR1 protein, human
negative cofactor 2 protein
down-regulator of transcription 1 protein, rat
transcription repressor NC2
Dr1 inhibitory factor
Dr1 protein, mouse
Dr1 protein, rat
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Type http://www.w3.org/2002/07/owl#Class

All Properties

altLabel
NC2 protein, mouse
NC2beta protein, mouse
down-regulator of transcription 1 protein, mouse
negative cofactor 2 beta, human
NC2-beta protein, human
down-regulator of transcription 1, TBP-binding (negative cofactor 2), human
NC2beta protein, human
DR1 protein, human
negative cofactor 2 protein
down-regulator of transcription 1 protein, rat
transcription repressor NC2
Dr1 inhibitory factor
Dr1 protein, mouse
Dr1 protein, rat
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prefLabel
down-regulator of transcription 1
II
D016385
Scope Statement
interacts with the TATA-binding protein; represses transcription; NC2 is identical to Dr1; RefSeq NM_026106 (mouse); NM_001938 (human); NM_001011914 (rat)
type
tui
T116
T123
HM
D014157
D010750
SC
1
TERMUI
T659877
T659885
T659880
T234537
T659878
T659876
T659886
T659884
T659879
T659875
T659874
T659882
T751711
T659883
T751712
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TH
NLM (2009)
NLM (2005)
NLM (1992)
SRC
Cell 1992 Aug 7;70(3):477-89
MMR
20090526
notation
C075995
Semantic type UMLS property
cui
C1667729
C0170954
C1664193
C0246873
MeSH Frequency
94
DSC
19920906
Inverse of RB
0
Mapped to
MDA
19920906
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