Medical Subject Headings

Last uploaded: March 22, 2026

Id	http://purl.bioontology.org/ontology/MESH/C000598573 http://purl.bioontology.org/ontology/MESH/C000598573
Preferred Name	1-(4-(4-(1-cyclopropylsulfonylcyclopropyl)-6-(3-methylmorpholin-4-yl)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea
Synonyms	AZD3147
Type	http://www.w3.org/2002/07/owl#Class

altLabel	AZD3147
prefLabel	1-(4-(4-(1-cyclopropylsulfonylcyclopropyl)-6-(3-methylmorpholin-4-yl)pyrimidin-2-yl)phenyl)-3-(2-hydroxyethyl)thiourea
Scope Statement	inhibits both mTORC1 and mTORC2; structure in first source
type	http://www.w3.org/2002/07/owl#Class
tui	T109 T121
Has mapping qualifier	http://purl.bioontology.org/ontology/MESH/Q000031
HM	D013890/Q000031 D011743
SC	1
TERMUI	T000881726 T000881725
TH	NLM (2015)
SRC	J Med Chem. 2015 Mar 12;58(5):2326-49.
MMR	20150611
notation	C000598573
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T109
cui	C4043853 C4045750
MeSH Frequency	2
DSC	20150611
Inverse of RB	0
Mapped to	http://purl.bioontology.org/ontology/MESH/D011743 http://purl.bioontology.org/ontology/MESH/D013890
MDA	20150611

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