Medical Subject Headings

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MESH/D015417
http://purl.bioontology.org/ontology/MESH/D015417
Preferred Name

Hereditary Sensory and Motor Neuropathy

Definitions
A group of slowly progressive inherited disorders affecting motor and sensory peripheral nerves. Subtypes include HMSNs I-VII. HMSN I and II both refer to CHARCOT-MARIE-TOOTH DISEASE. HMSN III refers to hypertrophic neuropathy of infancy. HMSN IV refers to REFSUM DISEASE. HMSN V refers to a condition marked by a hereditary motor and sensory neuropathy associated with spastic paraplegia (see SPASTIC PARAPLEGIA, HEREDITARY). HMSN VI refers to HMSN associated with an inherited optic atrophy (OPTIC ATROPHIES, HEREDITARY), and HMSN VII refers to HMSN associated with retinitis pigmentosa. (From Adams et al., Principles of Neurology, 6th ed, p1343)
Synonyms
Dejerine Sottas Disease
Hereditary, Type VII, Motor and Sensory Neuropathy
Proximal Hereditary Motor Neuropathy Type I
Dejerine Sottas Neuropathy
HMSN Type VIIs
Syndrome, Dejerine-Sottas
Hereditary Motor and Sensory Neuropathy
Dejerine-Sottas Syndrome
Dejerine-Sottas Neuropathy
Hereditary Motor and Sensory Neuropathy 3
HMSN Type IIIs
HMSN Type VII
Hereditary Motor and Sensory Neuropathies
Dejerine-Sottas Disease
Neuropathy, Dejerine-Sottas
Type VII, HMSN
Charcot-Marie-Tooth Disease, Type 3
Charcot-Marie-Tooth Disease, Demyelinating, Type 4f
HMSN Type III
Dejerine-Sottas Hypertrophic Neuropathy
Hereditary Motor and Sensory Neuropathy Type III
HMSN3
HMSN
Hypertrophic Neuropathy of Dejerine Sottas
Hypertrophic Neuropathy of Dejerine-Sottas
Dejerine Sottas Syndrome
Hereditary, Type III, Motor and Sensory Neuropathy
Disease, Dejerine-Sottas
Charcot Marie Tooth Disease, Type 3
Herditary Sensory and Motor Neuropathy
Neuropathies, Hereditary Motor and Sensory
CMT4f
HMN (Hereditary Motor Neuropathy) Proximal Type I
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