MedlinePlus Health Topics

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MEDLINEPLUS/C1428184
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1428184
Preferred Name

vitamin K 1 2,3-epoxide reductase subunit 1

Definitions
The VKORC1 gene provides instructions for making a vitamin K epoxide reductase enzyme. The VKORC1 enzyme is made primarily in the liver. It spans the membrane of a cellular structure called the endoplasmic reticulum, which is involved with protein processing and transport. The VKORC1 enzyme helps turn on (activate) clotting proteins in the pathway that forms blood clots. Specifically, the VKORC1 enzyme converts one form of vitamin K into a different form of vitamin K that assists in activating clotting proteins.
Synonyms
VKOR
VKORC1
FLJ00289
vitamin K epoxide reductase complex, subunit 1
vitamin K epoxide reductase complex subunit 1
Type http://www.w3.org/2002/07/owl#Class
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