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MedlinePlus Health Topics
Last uploaded:
March 22, 2026
| Id | http://purl.bioontology.org/ontology/MEDLINEPLUS/C1418707
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1418707
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|---|---|
| Preferred Name | polynucleotide kinase 3'-phosphatase |
| Definitions |
The PNKP gene provides instructions for making the polynucleotide kinase-phosphatase (PNKP) enzyme. This enzyme is critical for repairing broken strands of DNA molecules. It can help fix damage that affects one DNA strand (single-strand breaks) or both strands (double-strand breaks). At the site of the damage, the PNKP enzyme modifies the broken ends of the DNA strands so that they can be joined back together.
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| Synonyms |
Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP)
MCSZ
DNA 5'-kinase/3'-phosphatase
bifunctional polynucleotide phosphatase/kinase
AOA4
PNKP
PNK
EIEE10
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The PNKP gene provides instructions for making the polynucleotide kinase-phosphatase (PNKP) enzyme. This enzyme is critical for repairing broken strands of DNA molecules. It can help fix damage that affects one DNA strand (single-strand breaks) or both strands (double-strand breaks). At the site of the damage, the PNKP enzyme modifies the broken ends of the DNA strands so that they can be joined back together. |
|---|---|
| altLabel |
Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP)
MCSZ
DNA 5'-kinase/3'-phosphatase
bifunctional polynucleotide phosphatase/kinase
AOA4
PNKP
PNK
EIEE10
See more
See less
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| prefLabel | polynucleotide kinase 3'-phosphatase
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| DB XR ID | NCBI Gene:11284~OMIM:605610
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| Has associated condition | |
| type | |
| tui | T028
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| notation | C1418707
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| Semantic type UMLS property | |
| cui | C1418707
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