MedlinePlus Health Topics

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MEDLINEPLUS/C1414209
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1414209
Preferred Name

dysferlin

Definitions
The DYSF gene provides instructions for making a protein called dysferlin. This protein is found in the thin membrane called the sarcolemma that surrounds muscle fibers. Dysferlin is thought to aid in repairing the sarcolemma when it becomes damaged or torn due to muscle strain. Researchers suggest that dysferlin may also be involved in the formation of new muscle fibers (regeneration) and in inflammation, but little is known about these functions.
Synonyms
DYSF_HUMAN
DYSF
FLJ00175
fer-1-like protein 1
dystrophy-associated fer-1-like 1
FLJ90168
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
FER1L1
LGMD2B
Type http://www.w3.org/2002/07/owl#Class
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