MedlinePlus Health Topics

Last uploaded: March 22, 2026
Id http://purl.bioontology.org/ontology/MEDLINEPLUS/C1413938
http://purl.bioontology.org/ontology/MEDLINEPLUS/C1413938
Preferred Name

doublecortin

Definitions
The DCX gene provides instructions for producing a protein called doublecortin. This protein is involved in the movement of nerve cells (neurons) to their proper locations in the developing brain, a process called neuronal migration. Doublecortin attaches (binds) to microtubules, which are rigid, hollow fibers that make up the cell's structural framework (the cytoskeleton). The binding of doublecortin promotes the stability of microtubules. Microtubules help propel neurons by forming scaffolding within the cell that elongates in a specific direction, altering the cytoskeleton and moving the neuron.
Synonyms
XLIS
DC
LISX
doublecortex
DCX_HUMAN
DBCN
lissencephalin-X
doublecortex; lissencephaly, X-linked (doublecortin)
DCX
Type http://www.w3.org/2002/07/owl#Class
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