| Definitions |
Acute renal failure (ARF) is characterized by a relatively rapid decline in renal function that leads to the accumulation of water, crystalloid solutes, and nitrogenous metabolites in the body. Other clinical features include: increase in serum creatinine and urea nitrogen levels (azotemia) greater than 0.5 and 10 mg per deciliter, respectively; oliguria; and changes in the rate of urine flow. ARF may present with a de novo onset in individuals whose baseline renal function was within normal limits. Additionally, ARF may consist of acute exacerbation of pre-existing chronic renal insufficiency.
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| definition |
Acute renal failure (ARF) is characterized by a relatively rapid decline in renal function that leads to the accumulation of water, crystalloid solutes, and nitrogenous metabolites in the body. Other clinical features include: increase in serum creatinine and urea nitrogen levels (azotemia) greater than 0.5 and 10 mg per deciliter, respectively; oliguria; and changes in the rate of urine flow. ARF may present with a de novo onset in individuals whose baseline renal function was within normal limits. Additionally, ARF may consist of acute exacerbation of pre-existing chronic renal insufficiency.
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| Scope Statement |
NOTE: In Version 18.0, PT Fractional excretion of sodium was added as a broad scope term to Acute renal failure (SMQ), as an exception to the exclusion criterion "Normal and unspecified investigational terms." Fractional excretion of sodium assessment is useful in the evaluation of acute renal failure to determine whether renal failure is due to pre-renal, post-renal, or intrinsic renal pathology. PT Fractional excretion of sodium is thus of potential relevance for inclusion in this SMQ for the identification of cases of acute renal failure.
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