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Kidney Tissue Atlas Ontology
Last uploaded:
March 16, 2024
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| Id | http://purl.obolibrary.org/obo/MONDO_0004949
http://purl.obolibrary.org/obo/MONDO_0004949
|
|---|---|
| Preferred Name | neoplasm of mature B-cells |
| Definitions |
A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
Editor note: is a non-hodgkin in ONCOTREE
|
| Synonyms |
mature B-cell neoplasms
mature B-cell lymphocytic neoplasm
mature B-cell neoplasm
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
neoplasm of mature B-cells
|
|---|---|
| comment |
Editor note: is a non-hodgkin in ONCOTREE
|
| prefLabel |
neoplasm of mature B-cells
|
| exactMatch | |
| database_cross_reference |
DOID:706
SCTID:269476000
EFO:0000096
ICD9:202.0
NCIT:C27910
UMLS:C1334633
ONCOTREE:MBN
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|
| notation |
MONDO:0004949
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| has related synonym |
mature B-cell neoplasms
|
| id |
MONDO:0004949
|
| disease arises from structure | |
| textual definition |
A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
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| subClassOf | |
| imported from | |
| closeMatch | |
| type | |
| has exact synonym |
mature B-cell lymphocytic neoplasm
mature B-cell neoplasm
|
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