loading...| Preferred Name |
neoplasm of mature B-cells |
|
| Synonyms |
mature B-cell neoplasms mature B-cell lymphocytic neoplasm mature B-cell neoplasm |
|
| Definitions |
A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). Editor note: is a non-hodgkin in ONCOTREE |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0004949 |
|
| comment |
Editor note: is a non-hodgkin in ONCOTREE |
|
| closeMatch |
http://identifiers.org/snomedct/46744002 http://identifiers.org/snomedct/40411000 http://linkedlifedata.com/resource/umls/id/CL448793 |
|
| database_cross_reference |
DOID:706 SCTID:269476000 EFO:0000096 ICD9:202.0 NCIT:C27910 UMLS:C1334633 ONCOTREE:MBN |
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| disease arises from structure | ||
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C1334633 http://purl.obolibrary.org/obo/NCIT_C27910 |
|
| has exact synonym |
mature B-cell lymphocytic neoplasm mature B-cell neoplasm |
|
| has related synonym |
mature B-cell neoplasms |
|
| id |
MONDO:0004949 |
|
| imported from | ||
| label |
neoplasm of mature B-cells |
|
| notation |
MONDO:0004949 |
|
| prefLabel |
neoplasm of mature B-cells |
|
| textual definition |
A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/MONDO_0004949 | MONDO | SAME_URI | |
| http://purl.obolibrary.org/obo/MONDO_0004949 | OBA | SAME_URI | |
| http://purl.obolibrary.org/obo/MONDO_0004949 | DOVES | SAME_URI | |
| http://purl.obolibrary.org/obo/MONDO_0004949 | OBA | LOOM | |
| http://www.ebi.ac.uk/efo/EFO_0000096 | EFO | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0004949 | MONDO | LOOM | |
| http://purl.obolibrary.org/obo/MONDO_0004949 | DOVES | LOOM |