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Interaction Network Ontology
Last uploaded:
March 27, 2022
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| Id | http://purl.obolibrary.org/obo/GO_0006915
http://purl.obolibrary.org/obo/GO_0006915
|
|---|---|
| Preferred Name | apoptotic process |
| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
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| Synonyms |
activation of apoptosis
apoptosis signaling
type I programmed cell death
apoptotic program
apoptosis
apoptotic programmed cell death
apoptotic cell death
programmed cell death by apoptosis
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
apoptotic process
|
|---|---|
| prefLabel |
apoptotic process
|
| notation |
GO:0006915
|
| has_narrow_synonym |
activation of apoptosis
apoptosis signaling
type I programmed cell death
apoptotic program
apoptosis
|
| id |
GO:0006915
|
| has_obo_namespace |
biological_process
|
| textual definition |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
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| subClassOf | |
| imported from | |
| type | |
| has_exact_synonym |
apoptotic programmed cell death
apoptotic cell death
programmed cell death by apoptosis
|
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