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loading...| Preferred Name | Ivermectin [Chemical/Ingredient] | |
| Synonyms |
|
|
| ID |
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006374 |
|
| code |
C23096 |
|
| Display_Name |
Ivermectin |
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| imported from | ||
| label |
Ivermectin [Chemical/Ingredient] |
|
| MeSH_CUI |
M0011815 |
|
| MeSH_Definition |
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form. |
|
| MeSH_DUI |
D007559 |
|
| MeSH_Name |
Ivermectin |
|
| NUI |
N0000006374 |
|
| prefixIRI |
NDF-RT:N0000006374 |
|
| prefLabel |
Ivermectin [Chemical/Ingredient] |
|
| RxNorm_CUI |
6069 |
|
| RxNorm_Name |
Ivermectin |
|
| UMLS_CUI |
C0022322 |
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| subClassOf |
Create mapping
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006374 | CIDO | SAME_URI | |
| http://purl.bioontology.org/ontology/NDFRT/N0000006374 | NDFRT | LOOM | |
| http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000006374 | CIDO | LOOM |