Preferred Name

non-nucleoside Reverse Transcriptase Inhibitor
Synonyms

non-nucleoside Reverse Transcriptase Inhibitors

NNRTI

NNRTIs

Definitions

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors,[1] and cancer.[2] RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce. ... Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are the third class of antiretroviral drugs that were developed. In all cases, patents remain in force until beyond 2007. This class of drugs was first described at the Rega Institute for Medical Research (Belgium) Efavirenz Efavirenz has the trade names Sustiva and Stocrin. Nevirapine Nevirapine has the trade name Viramune. Delavirdine Delavirdine, currently rarely used, has the trade name Rescriptor. Etravirine Etravirine has the trade name Intelence, and was approved by the FDA in 2008. source: http://en.wikipedia.org/wiki/NNRTI

ID

http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001108

definition

Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors,[1] and cancer.[2] RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce. ... Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are the third class of antiretroviral drugs that were developed. In all cases, patents remain in force until beyond 2007. This class of drugs was first described at the Rega Institute for Medical Research (Belgium) Efavirenz Efavirenz has the trade names Sustiva and Stocrin. Nevirapine Nevirapine has the trade name Viramune. Delavirdine Delavirdine, currently rarely used, has the trade name Rescriptor. Etravirine Etravirine has the trade name Intelence, and was approved by the FDA in 2008. source: http://en.wikipedia.org/wiki/NNRTI

exact_synonym

non-nucleoside Reverse Transcriptase Inhibitors

NNRTI

NNRTIs

label

non-nucleoside Reverse Transcriptase Inhibitor

prefixIRI

hupson:SCAIVPH_00001108

prefLabel

non-nucleoside Reverse Transcriptase Inhibitor

subClassOf

http://purl.obolibrary.org/obo/CHEBI_35222

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