Human Physiology Simulation Ontology

Last uploaded: April 7, 2014

Id	http://purl.obolibrary.org/obo/CHEBI_367163 http://purl.obolibrary.org/obo/CHEBI_367163
Preferred Name	darunavir
Definitions	An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. source: http://purl.obolibrary.org/obo/CHEBI_367163
Synonyms	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate DRV Darunavir TMC114
Type	http://www.w3.org/2002/07/owl#Class

definition	An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. source: http://purl.obolibrary.org/obo/CHEBI_367163
label	darunavir
prefLabel	darunavir
exact_synonym	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate DRV Darunavir TMC114
prefixIRI	obolibrary:CHEBI_367163
subClassOf	http://www.co-ode.org/ontologies/galen#Drug
type	http://www.w3.org/2002/07/owl#Class
source	http://purl.obolibrary.org/obo/CHEBI_367163

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