Preferred Name |
No preferred name provided for selected language
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Synonyms |
systemic vasculitis angiitis vasculitis |
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Definitions |
A group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease. see infosheet: http://www.vasculitis.org.uk/content/downloads/understanding-vasculitis-factsheet-june-2014.pdf |
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ID |
http://www.ebi.ac.uk/efo/EFO_0006803 |
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comment |
see infosheet: http://www.vasculitis.org.uk/content/downloads/understanding-vasculitis-factsheet-june-2014.pdf |
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bearer_of | ||
closeMatch | ||
database_cross_reference |
MeSH:D014657 MedDRA:10047115 OMIM:615688 SNOMEDCT:31996006 Wikipedia:Vasculitis NCIt:C26912 DOID:865 ICD10:M31 NCIT:C26912 MESH:D014657 MONDO:0018882 Orphanet:280369 MedDRA:10036023 NORD:1823 UMLS:C0042384 GARD:18844 Orphanet:52759 SCTID:31996006 |
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definition |
A group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease. |
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exactMatch |
http://purl.obolibrary.org/obo/DOID_865 http://identifiers.org/mesh/D014657 http://linkedlifedata.com/resource/umls/id/C0042384 http://purl.obolibrary.org/obo/NCIT_C26912 |
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gwas_trait |
true |
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has_exact_synonym |
vasculitis |
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has_narrow_synonym |
systemic vasculitis |
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has_related_synonym |
angiitis |
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id |
EFO:0006803 |
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in_subset |
http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#orphanet_rare http://purl.obolibrary.org/obo/mondo#gard_rare http://purl.obolibrary.org/obo/mondo#disease_grouping http://purl.obolibrary.org/obo/mondo#ordo_group_of_disorders |
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label |
vasculitis |
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narrowMatch | ||
notation |
EFO:0006803 |
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term editor |
Sirarat Sarntivijai |
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subClassOf |