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Human Reference Atlas
Last uploaded:
January 7, 2025
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| Id | http://purl.obolibrary.org/obo/UBERON_0005408
http://purl.obolibrary.org/obo/UBERON_0005408
|
|---|---|
| Preferred Name | circumventricular organ |
| Definitions |
Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow.
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| Synonyms |
circumventricular organ of neuraxis
circumventricular organ
CVO
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. |
|---|---|
| altLabel |
circumventricular organ of neuraxis
circumventricular organ
CVO
|
| prefLabel |
circumventricular organ
|
| label |
circumventricular organ
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| database_cross_reference |
neuronames:1242
MESH:D066280
EMAPA:35243
BTO:0006267
NLXANAT:20090312
Wikipedia:Circumventricular_organs
FMA:84081
MA:0002942
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|
| notation |
UBERON:0005408
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| in_subset | |
| id |
UBERON:0005408
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| has_obo_namespace |
uberon
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| depiction | |
| structure_notes |
CVOs contain neural tissue and are an integral part of neuroendocrine function; all of the CVOs, besides the subcommissural organ, contain extensive vasculature and fenestrated capillaries which leads to a leaky BBB at the site of the organs; the lack of a BBB allows CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances
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| taxon_notes |
All vertebrates possess at least 4 circumventricular organs (including the hypothalamus) which can monitor the contents of the cerebrospinal fluid and secrete additional substances into it. (Butler, 1996, p. 330)
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| subClassOf | |
| type | |
| has exact synonym |
circumventricular organ of neuraxis
circumventricular organ
CVO
|
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