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Human Reference Atlas
Last uploaded:
January 7, 2025
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| Id | http://purl.obolibrary.org/obo/UBERON_0001288
http://purl.obolibrary.org/obo/UBERON_0001288
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|---|---|
| Preferred Name | loop of Henle |
| Definitions |
The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine.
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| Synonyms |
Henle's loop
ansa nephroni
Henle loop
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The section of the renal tubule in the kidney medulla with a hairpin bend; consists of a descending limb and an ascending limb, and is situated between the proximal convoluted tubule to the distal convoluted tubule; it functions to reabsorb water and ions from the urine. |
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| altLabel |
Henle's loop
ansa nephroni
Henle loop
|
| prefLabel |
loop of Henle
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| label |
loop of Henle
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| database_cross_reference |
Wikipedia:Loop_of_Henle
SCTID:361335009
VHOG:0001270
EMAPA:19280
UMLS:C0023986
MESH:D008138
BTO:0004608
NCIT:C33006
EV:0100390
FMA:17698
GAID:437
MA:0001675
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| notation |
UBERON:0001288
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| in_subset | |
| editor note |
the definitions of some kidney parts (e.g. proximal straight tubule) refer to Henle's loop, even in species where this may not be present. Requires review.
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| id |
UBERON:0001288
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| has_obo_namespace |
uberon
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| depiction | |
| taxon_notes |
The structure differs considerably between species; there is a definite physical loop of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus. However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of the mammalian loop of Henle were found to be present in the pronephros of the frog larva .
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| external_definition |
A highly specialized segment of the mammalian kidney tubules, that dips into the medulla. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, p.648, see_Liem_KF][VHOG]
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| function_notes |
The loop of Henle plays an important role in creating a concentration gradient in the medulla of the kidney. It is involved in reabsorption of filtered water and ions including sodium, potassium and calcium, and independently regulates both the volume and osmolarity of body fluids.
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| present in taxon | |
| dubious for taxon | |
| subClassOf | |
| type | |
| has exact synonym |
Henle's loop
ansa nephroni
Henle loop
|
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