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Human Reference Atlas
Last uploaded:
January 7, 2025
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| Id | http://purl.obolibrary.org/obo/UBERON_0000948
http://purl.obolibrary.org/obo/UBERON_0000948
|
|---|---|
| Preferred Name | heart |
| Definitions |
A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
|
| Synonyms |
branchial heart
cardium
vertebrate heart
chambered heart
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. |
|---|---|
| ccf_pref_label |
heart
|
| altLabel |
branchial heart
cardium
vertebrate heart
chambered heart
|
| prefLabel |
heart
|
| label |
heart
|
| comment |
Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706
|
| database_cross_reference |
galen:Heart
SCTID:302509004
CALOHA:TS-0445
MAT:0000036
XAO:0000064
TAO:0000114
MESH:D006321
EHDAA2:0000738
BTO:0000562
BILA:0000020
VHOG:0000276
NCIT:C12727
MIAA:0000036
UMLS:C0018787
ZFA:0000114
EFO:0000815
Wikipedia:Heart
EMAPA:16105
AAO:0010210
EHDAA:420
EV:0100018
FMA:7088
GAID:174
MA:0000072
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|
| notation |
UBERON:0000948
|
| in_subset |
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|
| ccf_asctb_type |
AS
|
| has_narrow_synonym |
branchial heart
|
| has_related_synonym |
cardium
|
| id |
UBERON:0000948
|
| has_obo_namespace |
uberon
|
| isDefinedBy | |
| part_of | |
| depiction | |
| has_relational_adjective |
cardiac
|
| external_definition |
Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]
Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]
|
| axiom_lost_from_external_ontology |
relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]
|
| homology_notes |
As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]
|
| present in taxon | |
| subClassOf | |
| type | |
| has exact synonym |
vertebrate heart
chambered heart
|
| ccf_is_provisional |
false
|
| ccf_part_of | |
| never in taxon | |
| treeView |
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