Link to this page
Human Reference Atlas
| Preferred Name | eosinophils | |
| Synonyms |
polymorphonuclear leukocyte polymorphonuclear leucocyte eosinophilic leukocyte eosinocyte eosinophilic granulocyte eosinophilic leucocyte |
|
| Definitions |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte. |
|
| ID |
http://purl.obolibrary.org/obo/CL_0000771 |
|
| comment |
Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.
|
|
| altLabel |
polymorphonuclear leukocyte polymorphonuclear leucocyte eosinophilic leukocyte eosinocyte eosinophilic granulocyte eosinophilic leucocyte
|
|
| ccf_ct_isa | ||
| ccf_is_provisional |
false
|
|
| ccf_located_in |
http://purl.obolibrary.org/obo/UBERON_0002370 http://purl.obolibrary.org/obo/UBERON_0002371 http://purl.obolibrary.org/obo/UBERON_0000399 http://purl.obolibrary.org/obo/UBERON_0015834 http://purl.obolibrary.org/obo/UBERON_0002124 http://purl.obolibrary.org/obo/UBERON_0002122 http://purl.obolibrary.org/obo/UBERON_0002125 http://purl.org/sig/ont/fma/fma7206 http://purl.obolibrary.org/obo/UBERON_0005483 http://purl.obolibrary.org/obo/UBERON_0000320 http://purl.obolibrary.org/obo/UBERON_0003988 https://purl.org/ccf/ASCTB-TEMP_lamina-propria-gut-associated-lymphoid-tissue-galt- http://purl.obolibrary.org/obo/UBERON_0002097 https://purl.org/ccf/ASCTB-TEMP_mucosa http://purl.org/sig/ont/fma/fma14966 http://purl.obolibrary.org/obo/UBERON_0002067 http://purl.obolibrary.org/obo/UBERON_0000178 http://purl.obolibrary.org/obo/UBERON_0002108 http://purl.obolibrary.org/obo/UBERON_0004791 http://purl.obolibrary.org/obo/UBERON_0002072 |
|
| ccf_pref_label |
eosinophil Eosinophil
|
|
| definition |
Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.
|
|
| has broad synonym |
polymorphonuclear leukocyte polymorphonuclear leucocyte
|
|
| has exact synonym |
eosinophilic leukocyte eosinocyte eosinophilic granulocyte eosinophilic leucocyte
|
|
| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas http://purl.obolibrary.org/obo/cl#blood_and_immune_upper_slim |
|
| isDefinedBy | ||
| label |
eosinophil
|
|
| prefixIRI |
CL:0000771
|
|
| prefLabel |
eosinophils eosinophil Eosinophil
|
|
| present in taxon | ||
| xRef |
CALOHA:TS-0279 MESH:D004804 BTO:0000399 FMA:62861
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |