Human Phenotype Ontology

Last uploaded: August 13, 2024
Preferred Name

Abnormal growth hormone level
Synonyms

Abnormal somatotropin level

Definitions

Any deviation from the normal level of growth hormone (GH) in the blood circulation. GH or somatotropin is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. Its secretion from the pituitary is regulated by the neurosecretory nuclei of the hypothalamus, which can release Growth hormone-releasing hormone (GHRH or somatocrinin) and Growth hormone-inhibiting hormone (GHIH or somatostatin) into the hypophyseal portal venous blood surrounding the pituitary. GH is secreted in a pulsatile manner, which is one of the reasons why an isolated measurement of its blood concentration is not meaningful.

ID

http://purl.obolibrary.org/obo/HP_0032367

dc_date

2019-02-23T18:15:25Z

definition

Any deviation from the normal level of growth hormone (GH) in the blood circulation. GH or somatotropin is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. Its secretion from the pituitary is regulated by the neurosecretory nuclei of the hypothalamus, which can release Growth hormone-releasing hormone (GHRH or somatocrinin) and Growth hormone-inhibiting hormone (GHIH or somatostatin) into the hypophyseal portal venous blood surrounding the pituitary. GH is secreted in a pulsatile manner, which is one of the reasons why an isolated measurement of its blood concentration is not meaningful.

has_exact_synonym

Abnormal somatotropin level

has_obo_namespace

human_phenotype

id

HP:0032367

label

Abnormal growth hormone level

notation

HP:0032367

prefLabel

Abnormal growth hormone level

terms_creator

https://orcid.org/0000-0002-0736-9199

treeView

http://purl.obolibrary.org/obo/HP_0003117

subClassOf

http://purl.obolibrary.org/obo/HP_0003117

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