Human Phenotype Ontology

Last uploaded: January 16, 2025
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Id http://purl.obolibrary.org/obo/HP_0031814
http://purl.obolibrary.org/obo/HP_0031814
Preferred Name

Palilalia
Definitions
Palilalia is the involuntary repetition of one's own phrases, words, or syllables 2 or more times in a row. Typically, palilalic utterances decrease in volume with the increasing number of repetitions. Sometimes, the repetitions are also uttered with an accelerating speed. In 1908, Souques first described palilalia in a patient with an ischemic stroke of the right hemisphere. Since then, palilalia, which is typically documented in up to a third of patients with Tourette syndrome was reported in patients with other neurodevelopmental disorders such as autism spectrum disorder or trisomy 16p and neurodegenerative disorders, such as progressive supranuclear palsy, dementia of the Alzheimer's type, valosin-containing-protein proteinopathy, or chorea-acanthocytosis. Focal brain lesions, typically affecting thalamic and/or midbrain structures, may also lead to the expression of palilalic behaviors. A family with extensive intracerebral calcification was reported to present palilalia, and indeed patients with Fahr syndrome, an etiologically heterogeneous disorder, will often present this clinical sign. Further, palilalia was reported as ictal, autoimmune, and drug-induced phenomenon (e.g., with clozapine or cefepime).
Type http://www.w3.org/2002/07/owl#Class

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definition

Palilalia is the involuntary repetition of one's own phrases, words, or syllables 2 or more times in a row. Typically, palilalic utterances decrease in volume with the increasing number of repetitions. Sometimes, the repetitions are also uttered with an accelerating speed.
label
Palilalia
comment
In 1908, Souques first described palilalia in a patient with an ischemic stroke of the right hemisphere. Since then, palilalia, which is typically documented in up to a third of patients with Tourette syndrome was reported in patients with other neurodevelopmental disorders such as autism spectrum disorder or trisomy 16p and neurodegenerative disorders, such as progressive supranuclear palsy, dementia of the Alzheimer's type, valosin-containing-protein proteinopathy, or chorea-acanthocytosis. Focal brain lesions, typically affecting thalamic and/or midbrain structures, may also lead to the expression of palilalic behaviors. A family with extensive intracerebral calcification was reported to present palilalia, and indeed patients with Fahr syndrome, an etiologically heterogeneous disorder, will often present this clinical sign. Further, palilalia was reported as ictal, autoimmune, and drug-induced phenomenon (e.g., with clozapine or cefepime).
prefLabel
Palilalia
notation
HP:0031814
id
HP:0031814
has_obo_namespace
human_phenotype
dc_date
2018-04-28T22:45:49Z
subClassOf
type
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