Human Phenotype Ontology

Last uploaded: August 13, 2024
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Preferred Name

Steroid-dependent nephrotic syndrome
Synonyms

SDNS
Definitions

A type of nephrotic syndrome in which two consecutive relapses (albumin urine dipstick at least 3+ or proteinuria greater than 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) occur during corticosteroid therapy, or within 14 days of ceasing therapy. Biopsy is necessary to determine underlying histology. Treatment with levamisole or immunosuppression (e.g. calcineurin inhibitors, cyclophosphamide or mycophenolat mofetil) in order to reduce steroid toxicity.
ID

http://purl.obolibrary.org/obo/HP_0025650
comment

Biopsy is necessary to determine underlying histology. Treatment with levamisole or immunosuppression (e.g. calcineurin inhibitors, cyclophosphamide or mycophenolat mofetil) in order to reduce steroid toxicity.
definition

A type of nephrotic syndrome in which two consecutive relapses (albumin urine dipstick at least 3+ or proteinuria greater than 40 mg/m2/d or urinary protein to creatinine ratio at least 2000 mg/g for 3 consecutive days) occur during corticosteroid therapy, or within 14 days of ceasing therapy.
has_exact_synonym

SDNS
has_obo_namespace

human_phenotype
id

HP:0025650
label

Steroid-dependent nephrotic syndrome
notation

HP:0025650
prefLabel

Steroid-dependent nephrotic syndrome
terms_creator

https://orcid.org/0000-0002-0736-9199
treeView

http://purl.obolibrary.org/obo/HP_0000100
subClassOf

http://purl.obolibrary.org/obo/HP_0000100
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