Human Phenotype Ontology

Last uploaded: July 1, 2024
Preferred Name

Abnormality of the intrinsic pathway

Synonyms
Definitions

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade. The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

ID

http://purl.obolibrary.org/obo/HP_0010989

comment

The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.

creation_date

2011-02-08T04:26:55Z

database_cross_reference

UMLS:C4023610

definition

An abnormality of the intrinsic pathway (also known as the contact activation pathway) of the coagulation cascade.

has_obo_namespace

human_phenotype

id

HP:0010989

label

Abnormality of the intrinsic pathway

notation

HP:0010989

prefLabel

Abnormality of the intrinsic pathway

terms_creator

https://orcid.org/0000-0002-0736-9199

treeView

http://purl.obolibrary.org/obo/HP_0003256

subClassOf

http://purl.obolibrary.org/obo/HP_0003256

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