Human Phenotype Ontology

Last uploaded: January 16, 2025
Id http://purl.obolibrary.org/obo/HP_0010546
http://purl.obolibrary.org/obo/HP_0010546
Preferred Name

Muscle fibrillation

Definitions
Fine, rapid twitching of individual muscle fibers with little or no movement of the muscle as a whole as ascertained by electromyography (EMG). If a motor neuron or its axon is destroyed, the muscle fibers it innervates undergo denervation atrophy. This leads to hypersensitivity of individual muscle fibers to acetyl choline so that they may contract spontaneously. Isolated activity of individual muscle fibers is generally so fine it cannot be seen through the intact skin, although it can be recorded as a short-duration spike in the EMG.
Synonyms
Twitching
EMG: fibrillations on electromyogram
Type http://www.w3.org/2002/07/owl#Class
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