Human Phenotype Ontology

Last uploaded: August 13, 2024
Preferred Name

Foam cells
Synonyms

Presence of foam cells

Foamy histiocytes

Foamy macrophages

Lipid-laden histiocytes

Definitions

The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance. Foam cells may contain polymorphic cytoplasmic inclusions consisting of lamellar osmiophilic membranes on electron microscopy.

ID

http://purl.obolibrary.org/obo/HP_0003651

comment

Foam cells may contain polymorphic cytoplasmic inclusions consisting of lamellar osmiophilic membranes on electron microscopy.

database_cross_reference

UMLS:C0016390

SNOMEDCT_US:16980002

definition

The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance.

has_alternative_id

HP:0003650

has_exact_synonym

Presence of foam cells

Foamy histiocytes

Foamy macrophages

Lipid-laden histiocytes

has_obo_namespace

human_phenotype

id

HP:0003651

label

Foam cells

notation

HP:0003651

prefLabel

Foam cells

treeView

http://purl.obolibrary.org/obo/HP_0002621

subClassOf

http://purl.obolibrary.org/obo/HP_0002621

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