Preferred Name

smad protein
Synonyms

SMAD

Definitions

A protein with core domain composition consisting of one MH1 domain (Pfam:PF03165) at the N terminus and one MH2 domain (Pfam:PF03166) at the C-terminus, separated by a non-conserved linker region. Smad proteins are mediators of signal transduction in transforming growth factor beta (TGF-beta) superfamily pathways.

ID

http://purl.obolibrary.org/obo/PR_000000027

Description

Smads is a conserved family of signal transducers. Functionally, Smads fall into three subfamilies:R-Smads; Co-Smads; I-Smads. Eight Smad proteins are encoded in vertebrate, four in Drosophila, and three in C. elegans.

Smads is a conserved family of signal transducers. Functionally, Smads fall into three subfamilies:R-Smads; Co-Smads; I-Smads. Eight Smad proteins are encoded in vertebrate, four in Drosophila, and three in C. elegans.

database cross reference

PIRSF:PIRSF037286

definition

A protein with core domain composition consisting of one MH1 domain (Pfam:PF03165) at the N terminus and one MH2 domain (Pfam:PF03166) at the C-terminus, separated by a non-conserved linker region. Smad proteins are mediators of signal transduction in transforming growth factor beta (TGF-beta) superfamily pathways.

has role

http://purl.bioontology.org/ontology/HOIP/HOIP_0003720

has_exact_synonym

SMAD

label

smad protein

prefixIRI

PR:000000027

prefLabel

smad protein

subClassOf

http://purl.obolibrary.org/obo/CHEBI_25367

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