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Homeostasis imbalance process ontology
Last uploaded:
April 3, 2024
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| Preferred Name | IFNG | |
| Synonyms |
IFN-gamma interferon gamma |
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| Definitions |
A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions. Note: Some references consider 'gamma' and 'type II' to be synonyms. This is likely because gamma is the only type II interferon identified. However, the classification criteria for each nomenclature system differ. |
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| ID |
http://purl.obolibrary.org/obo/PR_000000017 |
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| comment |
Note: Some references consider 'gamma' and 'type II' to be synonyms. This is likely because gamma is the only type II interferon identified. However, the classification criteria for each nomenclature system differ.
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| database cross reference |
NCBI-Human-GeneID:3458
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|
| definition |
A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions.
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| has_exact_synonym |
IFN-gamma interferon gamma
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| label |
IFNG
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| prefixIRI |
PR:000000017
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| prefLabel |
IFNG
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| subClassOf |
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