loading...| Preferred Name |
smooth endoplasmic reticulum |
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| Synonyms |
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| Definitions |
The hepatocyte is a cell with an abundant smooth ER. |
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| ID |
http://purl.obolibrary.org/obo/GO_0005790 |
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| comment |
The hepatocyte is a cell with an abundant smooth ER. |
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| contains process | ||
| database cross reference |
ISBN:0815332181 NIF_Subcellular:sao710427438 Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum |
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| definition |
The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. |
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| label |
smooth endoplasmic reticulum |
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| prefixIRI |
GO:0005790 |
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| prefLabel |
smooth endoplasmic reticulum |
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| subClassOf |