loading...| Preferred Name | Cogan Syndrome | |
| Synonyms |
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| Definitions |
Cogan syndrome (CS) is a rare autoimmune disorder of unknown origin characterized by inflammatory ocular disease (mainly interstitial keratitis) and vestibulo-auditory manifestations (mainly acute onset hearing loss, tinnitus and vertigo), in the setting of a negative work-up for syphilis, with a variable risk of developing into a systemic disease. Systemic manifestations may occur in more than 70% of cases. |
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| ID |
http://purl.obolibrary.org/obo/HIO_0000370 |
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| description |
Cogan syndrome (CS) is a rare autoimmune disorder of unknown origin characterized by inflammatory ocular disease (mainly interstitial keratitis) and vestibulo-auditory manifestations (mainly acute onset hearing loss, tinnitus and vertigo), in the setting of a negative work-up for syphilis, with a variable risk of developing into a systemic disease. Systemic manifestations may occur in more than 70% of cases. |
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| created_by |
Jade Hotchkiss |
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| creation_date |
2019-08-13T15:16:14.501377Z |
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| database cross reference |
ORPHA:1467 |
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| definition source | ||
| existence in other ontologies |
Sufficient |
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| hasExactSynonym |
Diffuse Interstitual Keratitis Cogan's Syndrome CS |
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| label |
Cogan Syndrome |
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| prefixIRI |
HIO:0000370 |
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| prefLabel |
Cogan Syndrome |
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| subClassOf |